I've made the point in numerous places that the photobiomodulation dose response curve is not like American capitalism, more is not always better. Here is a very good basic science example that helps support this view. Researchers used different amount of light energy on human skin cells to see how they'd respond. The key result was that the lower power settings produce the most positive change in cell proliferation activity. Majority people who are now using the Neuradiant 1070+, as well as the Vielight Neuro devices, report benefit from shorter periods of stimulation and do not experience any of the typical overdose responses including headaches, increased sense of congestion and pressure, agitation, irritability, dizziness, and fatigue. This has informed the Neuradiant's titration protocol to start with 3 minutes, then wait 5-10 minutes before continuing for another 3 minutes. The stimulation location, pulse frequency, and intensity are each both programmed based on clinical history, telehealth consultation and quantitative EEG analysis. The dosing schedule often increases over time and can even exceed 20 minutes in some cases to as much as 30 minutes twice daily but always with an eye to recognizing signs of overdose and then adjusting accordingly. PBM dosing is an evolving process and will become more specific as we evolve our real time neurometric acquisition and anlalytic capability.
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