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Leading Edge Commentary

November 01st, 2020

11/1/2020

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This study supports our view that diagnosis of neuropsychiatric and neurodegenerative conditions require ruling out any presence of tick borne diseases including Lyme and all co-infections, heavy metal and mold toxicity. Anyone who works outdoors or participates in field related sport activity who then develops PTSD should be checked for the presence of these neuroinfalmmatory agents. Traumatic events may trigger the expression of symptoms in those who are sufficiently compromised to impair full recovery. QMF has long employed and advocated for the use of Quantitative EEG and heart rate variability (HRV) indices as neuromarkers that allow empirically validated injury assessment, thus leading to highly individualized treatment planning and efficacy assessment.  
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The prevalence of Lyme disease and associated co-infections in people with a chronic post-concussive syndrome

Azzolino S, Zaman R, Hankir A, Carrick FR.
Psychiatria Danubina. 2019 Sep;31(Suppl 3):299-307.
https://www.ncbi.nlm.nih.gov/pubmed/31488744

Abstract
Introduction
There is increasing awareness that Lyme borreliosis (LB) and traumatic brain injury (TBI) may cause mental health symptoms. TBI and Lyme disease compromise the health and activities of millions of patients per year. The chronic symptoms and disability of TBI and Lyme disease share a similar clinical presentation. We have identified an alarming number of individuals suffering from post-concussion syndrome (PCS) that are refractory to care and that have serologically tested positive for Lyme disease.

Subjects and Methods

A single-center retrospective review of patient charts that were symptomatic a minimum of one year after a TBI that were tested for Lyme disease to ascertain if there was a relationship.

Results

217 PCS patient records (93 females with a mean age of 34 years, 120 males with a mean age of 40 years and 4 individuals with unknown gender) were included in the review. 38% had a positive Western Blot Igenex IgM. There was a statistically significant relationship of a positive Western Blot Igenex IGM predicting chronic PCS Pearson χ2(1)=6.8866, P=0.009, Fisher's exact score p=0.015 and φ=0.2813 representing a moderate effect size.

Conclusions

Long term PCS over one year's duration is associated with undiagnosed Lyme disease. There was statistical and substantive significance between individuals with chronic PCS having a positive Western Blot Igenex IgM. Males were more likely to have a positive Western Blot Igenex IgM than females.

Free, full text (pdf file):
http://www.psychiatria-danubina.com/UserDocsImages/pdf/dnb_vol31_sup3/dnb_vol31_sup3_299.pdf

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