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Leading Edge Commentary

Photobiomodulation Supports Glymphatic System Functioning

6/3/2022

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Photobiomodulation Therapy and the Glymphatic System: Promising Applications for Augmenting the Brain Lymphatic Drainage System
Article in International Journal of Molecular Sciences · March 2022
DOI: 10.3390/ijms23062975
This is an important resource for those who are working with people diagnosed with neurodegenerative, neuropsychiatric or neurodevelopmental challenges. The key points are that there is a drainage system for the central nervous system that can become blocked and this leads to development of cognitive and behavioral symptoms associated with neurodegenerative disorders, including Alzheimer's and Parkinson's disease. The glial cells that support and protect the neurons are supported by this system to provide a way to discharge waste products from the brain. Sleep has now been shown to be the key driver in supporting the efficient operation of the glymphatic system. 

Photobiomodulation is now been shown to positively influence the glymphatic processes by improving cortical perfusion and oxygenation as well as improving vascular flexibility of the brain's microcapillary system and acts to maintain, protect and optimize the clearance of neural waste products. Previous research has demonstrated that 1064nm stimulation is significantly more effective than 810nm wavelength at producing specific biological activity that is associated with both perfusion and tissue level oxygenation as well as improving cellular energy metabolism by increasing production of adenosine triphosphate (ATP) through accelerating neural and glial cell mitochondrial activation. 

The Neuradiant 1070 PBM helmet selectively delivers cortical 1070nm LED light stimulation to specific brain regions and can thereby provide effective penetration and cellular activation thus supporting the glymphatic drainage process. For more information on the Neuradiant 1070 see neuronic.online
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